这些是你的 Those are yours.
是我们一起买的 We bought them together.
因为你觉得「样式很舒心」 Because you "Found the pattern soothing."
我会想念你的 肖恩 I'm gonna miss you, Shaun.
我爱卡莉 I love Carly.
那太好了 And that's great.
我真为你感到高兴 I am so happy for you.
现在你想随时放错卷纸 Now you can hang the toilet paper incorrectly
都没人管你了 anytime you want.
我和卡莉也可以回到 And Carly and I can go back
我们吵架之前的状态 to the way things were before our fight.
有时候情侣间需要点时间恢复 Well, sometimes couples need a little time to recover.
我们不用 We won't.
卡莉要你搬出去 Carly asked for you to move out.
你要搬出去了 You are moving out.
我体内得有几个肾才能去参加毕业舞会 How many kidneys do I need in my body to attend prom?
瑞恩 Ryan...
即使我在手术中摘除了一个肾 Even if the surgery removes my kidney,
那也是个腹腔镜手术 it'll be laparoscopic,
所以我最多只要住院七天 so my inpatient time will be seven days, tops.
然后在家休养三天 And then three more days of rest at home.
我就可以带女朋友去毕业舞会了 对吗 I can take my girlfriend to prom, right?
那不完全是个医疗决定 That's not a purely medical decision.
我需要抽点血 I have to draw some blood.
梅伦德斯医生既能摘除肿瘤 What are the chances Dr. Melendez might be able
又能保住瑞恩的肾的几率有多大 to remove the tumor but spare Ryan's kidney?
核磁共振结果会告诉我们 Well, the MRI will let us know
化疗让肿瘤缩小了多少 how much the chemo shrunk the tumor,
但你不能抱太大希望 but you shouldn't count on it.
一个辣椒汉堡 多加黄芥末和腌菜 One chili burger, extra mustard, extra pickles.
早啊 库珀先生 Hi. Morning, Mr. Cooper.
我不确定他在术前能否吃这个 I'm not sure he can have that with his surgery...
今晚六点三十之前都可以的 Oh, he's fine until about 6:30 tonight.
我认识你 I know you.
安吉·瓦伦斯 Angie...Valens.
我帮你装过化疗用人工血管 I helped put in your chemo port.
感谢你救了我 I owe you a big thank-you.
我们在化疗时认识的 We met in chemo.
他们应该 They should put us in a
广播一下我们的故事 public service announcement or something.
像是「干掉肿瘤 抱得男友归 Yeah... "I lost a tumor and gained a boyfriend.
感谢化疗」 Thanks, chemo."
詹姆斯·麦克道格 James McDougall?
我们也是为他而来的 That's who we're here for, too.
你们都可以去四区 All of you can head over to Bay 4.
他在六个月前因骨裂来找过我 Guy saw me six months ago for a stress fracture.
他是个超级马拉松狂人 He's a lunatic ultra-marathoner.
我希望他别训练太猛 I just hope he didn't go too hard too soon
这么快又骨裂了 and break it again.
他没有再次骨裂 He didn't break it again.
良 医
第三季 第十二集
你的家庭医生让你用酮洛芬消肿是对的 Your GP was right to start you on ketoprofen for the swelling,
但显然不起作用 but clearly, it isn't working.
所以莫菲和雷兹尼克医生 That's why Drs. Murphy and Reznick
要堵住你的一些淋巴管 are going to block off some of your lymphatic channels.
应该能减少淋巴液分泌 It should reduce production.
但我们当前更担心的是病因 The more pressing concern is why.
你以前动过淋巴结手术吗 Have you ever had surgery on your lymph nodes?
抗癌治疗和放疗呢 What about cancer or radiation treatment?
没有 我在身体方面一直很健康 No. Physically, I've always been healthy.
身体方面 Physically?
我在十六岁时 I was diagnosed with
被确诊为持续性抑郁症 Persistent Depressive Disorder when I was 16.
所以你得让我重新回到跑道上 医生 That's why you got to get me back out on the road, Doc.
抗抑郁药对你无效吗 Are antidepressants not effective for you?
它们还是有效的 I mean, they help.
但跑步才是关键 But running really is key.
它拯救了我的婚姻 和我的生命 Saved my marriage and... my life.
淋巴肿大可能是由感染导致 Lymphedema can be caused by an infection.
但他没有发热症状 He doesn't have a fever.
酮洛芬能退热 Ketoprofen can suppress fevers.
我们去做个细菌培养 Let's get some cultures
让他开始服用广谱抗生素 and start him on broad-spec antibiotics.
照你说的 给你新的灌肠剂 As requested, your restock on enemas.
这个幌子不错 Nice cover.
你觉得怎么样 How've you been feeling?
甲氨蝶呤很有效 The methotrexate is working great.
没有疼痛 没有红肿 No pain, no redness.
浑身僵硬 类似流感症状呢 Stiffness, flu-like symptoms?
没有 一切正常 No. All good.
你还要靠给别人做类风湿性关节炎检查 How long are you planning to hide out doing RA exams
给糖尿病人剪脚趾甲逃避到什么时候 and clipping diabetics' toenails?
晕眩 头疼 恶心吗 Dizziness, headaches, nausea?
我 有时候我吃完东西会有点反胃 I... Sometimes I'm a little queasy after I eat.
你曾那么热爱神经外科 You had to love neurosurgery.
给你开一种 How about we try to get you a medication
不会刺激你胃的药怎么样 that doesn't irritate your stomach?
不用 我的手感觉很好 别的我都不在乎 No. My hands feel great. That's all I care about.
你曾经常做开颅手术 You used to open up skulls
做着复杂的脑部手术 and poke around people's brains.
你不可能满足于此 There's no way this fulfills you.
我乐在其中 I enjoy it.
或者 更确切地说 我通常很享受 Or, rather, I usually enjoy it.
我还是不打扰你了 I'll let you get back to it.
也许有人需要灌肠 Maybe someone out there needs an enema.
威尔姆斯瘤的大小确定了吗 Got a measurement on the Wilms tumor?
还需要些时间 Mm, not quite there yet.
你提到七厘米是我们 You mentioned 7 centimeters as our limit
做腹腔镜手术的极限 to doing this laparoscopically.
如果我们提高到七点二呢 What if we pushed it to 7.2?
可以加快恢复速度 Would speed up recovery.
加快几天而已 By a few days.
就当我没问 Forget I brought it up.
瑞恩想带他女朋友去毕业舞会的愿望 Ryan wanting to take his girlfriend to prom
不应该影响我们的手术计划 should not factor into our surgical plan.
他很喜欢她吗 Is he nuts about her?
简直疯狂 爱得死去活来 Ohh. Crazy, head over heels in love.
他们彼此都是 They both are.
白痴 Idiots.
我不介意再做一次那样的白痴 I wouldn't mind being an idiot like that again.
虽然 我不确定自己是否有过这种感觉 Though, I'm not sure I ever felt that way,
十分幸福 totally happy.
所以治疗进展顺利 So therapy's going well?
肺部无转移 No metastasis in the lungs.
看那个 Look at that.
你的肿瘤不见了 Your tumor is gone.
不见了 Gone?
这怎么可能 How's that possible?
化疗的效果比我们预期的要好 The chemotherapy worked better than we expected.
等等 没有肿瘤 一点没有 Wait, like, no tumor? Zero?
不需要做任何手术 No need for surgery whatsoever?
没错 That is right.
这些是出院手续 These are discharge forms.
我的两个肾都能带你去舞会 Both of my kidneys are taking you to prom!
太好了 Aah! Hell, yeah!
安吉 Angie?
-安吉 -她癫痫发作了 - Angie! - She's having a seizure!
两毫克劳拉西泮和便携式氧气 快 2 milligrams of lorazepam and portable oxygen, stat.
把那个拿来垫在她头下 Let's get that under her head.
他的肺里充满了液体 His lungs are filled with fluid.
我需要做胸部X光片和床旁超声 I need a chest X-ray and a bedside ultrasound.
呼叫雷兹尼克医生 And page Dr. Reznick.
影像检查证实 Imaging has confirmed the reoccurrence
你的脑瘤复发了 of your brain tumor.
什么阶段 What stage?
第三阶段 Three.
最好的方法是手术 The best approach is surgery,
大面积切除肿瘤 a wide resection of the tumor,
然后进行放疗和化疗 followed by radiation and chemo
以便完全恢复 to encourage full remission.
听起来要度过有趣的几个月 Sounds like a fun couple months.
全面恢复可能需要大约八个月的时间 Full recovery will probably take closer to eight.
我们能挺过去的 宝贝 就像上次一样 We can get through this, baby, just like last time.
手术什么时候进行 W-when will the surgery be?
我们需要做一些其他影像检查 We need to do some additional imaging,
我还要找医生会诊 and I'd like to consult a colleague
找到最佳的手术方法 about the best surgical approach.
这需要几天时间 That'll take a few days.
不着急 Take your time.
舞会呢 Prom?
对啊 Yeah.
现在瑞恩可以去了 我也得去 Now that Ryan can go, I have to go.
宝贝 Honey.
我们谈论的是你的健康 This is your health we're talking about.
妈妈 拜托 Mom, please.
我只想像个正常孩子一样去参加舞会 I just want to do this one thing like a normal kid.
快告诉她没问题的 Can you tell her it's okay?
不行 We can't.
在摘除肿瘤前 Until we remove your tumor,
你都有潜在致命癫痫发作的风险 you're at risk of potentially fatal seizures.
等你痊愈了 After you're recovered,
你和瑞恩可以收拾得漂漂亮亮的 you and Ryan can get all dressed up,
我们一起去盛景吃晚餐 好吗 and we'll go have dinner at the Grandview. Okay?
毕业舞会没劲透了 Prom sucks.
我兄弟弄了个假身份证明 My buddy had a fake ID.
我在豪车里喝到断片 I got so drunk in the limo that I passed out
压根没去舞会 and never made it into the dance.
或许不是所有人都这样 Maybe that wasn't everybody's experience.
我是舞会国王 我舞伴是舞会皇后 I was prom king. My date was queen.
我有裙子 也有舞伴 I had the dress, I had the date,
还有个被逮捕的妈妈 I had the mom who got arrested.
花了一晚上把她从醉汉监禁室里捞出来 Spent the night picking her up from the drunk tank.
你在那看见朴了吗 Did you see Park while you were there?
去安排时间 把安吉的手术安排在周五 Go to scheduling, get Angie's surgery set for Friday
要最好的神经外科手术护士 with the best neurosurgery OR nurses.
走 去看看格拉斯曼 Let's go see Glassman.
现在我在检查 Now I'm identifying
亚毫米淋巴管 the submillimeter lymphatic vessels.
我需要11-0微米缝合线和70微米的针 I need an 11-0 micro suture and a 70 micron needle.
与其摘除这部分的淋巴结 Instead of harvesting nodes to this area,
能不能把淋巴管从淋巴系统中分离 could we redirect lymphatics away from his lymph system?
可以 We could.
如果你能找到一条合适的血管 If you identify an appropriate vessel,
就可以把二者缝合在一起 you can make the connection.
显然不是某处有感染 We're clearly not dealing with an infection.
他的淋巴系统中肯定哪里被堵住了 There must be a blockage somewhere in his lymph system.
很像是癌症 Most likely cancer.
他的血常规检测显示细胞一切正常 His CBC didn't show any abnormal cells.
淋巴瘤有时候查不出来 Lymphoma doesn't always show up.
得给他的淋巴液做细胞化学检查 We need to run cytology on his lymphatic fluid.
情况会变得糟糕或非常糟糕 It's either gonna be nasty or very nasty,
取决于肿瘤是如何附着在 depending upon how it attaches
丘脑和穹隆上的 to the thalamus and fornix.
而这是做影像或检查无法确定的 Which no imaging or testing can possibly determine.
我们的方案是什么 So, our options are?
在做内窥镜或开前叶里选一个 Between an endoscopic approach or an open anterior one.
没错 That is correct.
我会给她做个基点立体磁共振和弥散张量成像 I'd run a stereotactic MRI with fiducials and DTI
以测量白质束具体离得有多近 to gauge how close the white matter tracts actually are.
你应该刷手做手术 You should scrub in.
可以找个医生顶替诊所的活 Another doctor can cover the clinic.
我已经一年没进手术室了 I haven't been in an OR in over a year,
后来我还成了病患 and then, as a patient.
我不是让你来主刀 I'm not asking you to cut.
但你在场会很有帮助 But it'd be a huge value to have you there.
谢谢 I appreciate that.
我会考虑的 I'll consider it.
你好 我们需要给淋巴液做细胞化学检查 Hello. We need to run cytology on this lymphatic fluid.
很高兴为你服务 I would be happy to.
莉亚今早搬走了 Lea moved out this morning.
-谢谢 -不客气 - Thank you. - You're welcome.
你今晚能过来吗 Can you come over tonight?
可能不行 Uh, that probably won't work...
或者我们去你的公寓 Or we could go to your apartment?
不行 I can't.
莉亚说修复我们的关系 Lea said that it might take time
需要一段时间 for us to recover from our fight.
但我告诉她我们没事 But I told her that we were okay.
的确 We are.
我今晚有计划了 I made plans tonight.
和我一个刚被解雇的朋友聊聊 To hang out with a friend who just got fired.
但我很想明晚去 But I would love to come over tomorrow night.
好啊 Okay.
这个检测我也会尽快做好的 I'll put a rush on this test, too.
你淋巴静脉吻合术的手法 Your lymphovenous anastomosis technique...
让我五体投地 I was impressed.
你这马屁拍得未免太早了 It's a little early in the morning
雷兹尼克 to be sucking up, Reznick.
没有 我是喜欢有话直说 Not for me. I like to get a jump on things.
你在做其他外科手术时用到了 I'm fascinated by the way you use plastic procedures,
显微手术等整形手术法 我被惊艳到了 like microsurgery, in other surgical specialties.
我觉得我可能发现了一个有意思的论文选题 I thought it might make an interesting topic for a paper.
想和我一起写吗 Want to write it with me?
好啊 Yes.
我们边吃边聊 Let's talk and eat.
早餐不能就吃这个 That's not breakfast.
我请你 I'm buying.
你想选哪家出版社 What publications do you want to target?
上次 安吉术后呕吐严重 Last time, Angie had bad post-op vomiting.
-好的 我记下来 -不好意思 - Of course. I'll make note of it... - Excuse me.
她睡着了 她需要休息 She's asleep. She needs her rest.
我在外面等她醒 I'll wait out here until she's awake.
瑞恩 你的免疫系统很弱 Ryan, your immune system is weak.
你很容易 It would be so easy for
染上病然后传染给安吉 you to pick up a bug and pass it to Angie.
我发誓 我只跟我爸爸接触过 I haven't been around anyone but my dad. I swear.
他可以戴个口罩 He could wear a mask.
安吉手术后 我们会安排让你探视的 After Angie's surgery, we'll see about arranging a visit.
请转告她瑞恩来过 Please tell her Ryan came by.
如果我过界了 我很抱歉 I'm sorry if I overstepped.
我想把安吉的病历 I'd like to change Angie's status
改为「谢绝探视」 to "No visitors" on her chart.
好的 Yeah.
请带麦克道格先生回房间 Please take Mr. McDougall to his room.
我一会儿就来 I'll be there in a moment.
那是詹姆斯·麦克道格吗 Is that James McDougall?
-和他在一起的那个女人呢 -他的妻子 - And the woman with him? - His wife.
癌症吗 Is it cancer?
不 更糟 No... Worse.
他的淋巴水肿是由基因突变引起的 His lymphedema is caused by a genetic mutation.
如果你不能给他找到有效的药 If you don't find a medication he responds to,
他会体内窒息而死的 he'll drown from the inside.
詹姆斯的序列基因发生突变 The mutation is on James' ARAF gene.
产生一种叫做激酶的酶 It makes an enzyme called kinase,
会导致细胞过度增殖 which can cause cells to overproliferate.
这是种遗传病 It's a genetic condition.
什么引起的 What set it off now?
可能是应力骨折 Probably the stress fracture.
导致他的免疫系统过劳运作 Sent his immune system into overdrive,
刺激了他的淋巴系统 which fired up his lymphatic system.
针对这种突变的治疗方案是什么 What treatment protocol targets this mutation?
用甲基乙基酮抑制剂 An MEK inhibitor.
问题是 用哪一种 The problem is, which one?
有41种 There are 41 possibilities,
每种都有不同的副作用 each with different side effects.
祝你们好运 Good luck.
我希望你能留下来 Well, I was hoping you could stay.
好 可以 Okay. Sure.
我们需要你保持不动 We need you to stay completely still.
没问题 Not a problem.
你还好吧 You okay?
瑞恩彻底抛弃我了 Ryan totally bailed.
他没有回来看我 He hasn't come back to see me.
如果你告诉她是她妈不让他来探视 If you tell her that her mom said he couldn't visit,
她会生她妈妈的气 she'll be pissed at her mom.
这样做有什么好处 How's that gonna help?
他可能在学校忙 He's probably busy catching up in school.
我们有约定 We had a pact.
只要我们在一起 癌症就打不垮我们 As long as we were together, cancer wasn't gonna beat us.
他失言了 He broke it.
癌症赢了 Cancer wins.
你可以自己完成吧 Do you mind finishing?
造影结束了吗 Imaging finished?
还没有 Not quite.
瓦伦斯太太 安吉很想见瑞恩 Mrs. Valens, Angie would really like to see Ryan.
我知道你担心感染 I know you're concerned about infection,
但风险很小 but there is minimal risk.
实际上 如果他们只是视频聊天完全没风险 Actually... actually, none, if they do a video chat.
好主意 Interesting idea.
我会考虑的 I'll think about it.
安吉很沮丧 Angie's depressed.
研究表明 And studies have shown that
沮丧会对她的手术结果 that can have a negative impact
产生负面影响 on her surgical outcome.
瑞恩并不会一直让安吉开心 Ryan doesn't always improve Angie's mood.
几周前 他们吵了一架 A couple of weeks ago, they had some silly fight,
她哭了好几天 and she cried for days.
谢谢你跟我说这些 Thank you for letting me know.
我会尽力让她高兴起来 I'm gonna do my best to cheer her up.
她才十六岁 She's a 16-year-old.
她需要她的男朋友 She wants her boyfriend.
是啊 Yeah.
你十六岁的时候有多聪明呢 And how smart were you when you were 16?
塞卢美替尼怎么样 Well, what about Selumetinib?
它治疗相关症状的效果很好 It's shown promising results on related conditions.
也很有可能造成肝脏疾病 And a high occurrence of liver disease.
比尼梅替尼也差不多 但并发症少一些 Binimetinib is similar, but has fewer complications.
有人反对吗 Any objections?
那就先给詹姆斯试试 Let's start James on that.
一起工作感觉太棒了 This is exciting, working together.
是啊 It is.
但我习惯了 Although, I'm used to
面对样品和切片而不是病人 samples and slides instead of patients.
病人有时候很难搞定 Patients can be difficult.
但你会习惯的 But you will be fine.
你需要什么吗 Do you need something?
我只是好奇比尼梅替尼 I was curious how James was responding
对詹姆斯效果如何 to the Binimetinib.
他的尿量增多了 His urine output is up,
这表示他的淋巴液 which suggests the lymphatic fluid...
以及钾的含量偏低 and his potassium is a little low.
你能把这个给他吗 Can you...give him this?
我不是要... I wasn't really...
你好 我是莱瓦医生 Hi. I'm Dr. Lever.
肿瘤紧挨着甚至可能渗入了 The tumor's abutting and possibly infiltrating
她脑穹庐的白质束 the white matter tracts of her fornix.
所以我们很可能得切除一部分 We'll likely have to remove a section.
这会影响到她的记忆能力 That'll affect her ability to form memories.
通过神经心理学康复 With a lot of neuropsych rehab,
她也许能用其他的途径来弥补 she may be able to compensate with other pathways.
研究表明 Studies have shown that
积极的态度更利于得到积极的结果 positive attitudes lead to positive outcomes.
你在担心她的态度 You're worried about her attitude?
她在担心年轻人的爱情 She's worried about young love.
我在担心安吉手术后要面对的事 I'm worried about what Angie is facing after surgery.
理疗 认知治疗 Physical therapy, cognitive therapy,
一个接一个的挑战 one challenge after another.
而她想要的其实很简单 And what she wants is so simple.
你想让一个难过的孩子开心 You want to make a sad kid happy?
我想是的 I guess I do.
这不是我的工作 Which isn't my job, and I need to stop
我也确实不能再卷入别人的私事了 getting sucked into people's personal issues.
能在不让她妈妈 Is there a way to do that without
反感的情况下做到吗 antagonizing the mother?
可能吧 Maybe.
那就让她开心点 Then make her happy.
我们从来没做到过这一步 We've never gotten this far before.
没有 No.
我们没有 We haven't.
你还好吗 And you're okay?
我非常好 I am very okay.
卡莉 Carly.
等等 Okay.
我做错什么了吗 Did...I do something wrong?
不 对不起 是因为我 No, I'm sorry. It's me.
你说过我们没事 You said we were okay.
我以为没事 I thought we were.
我想让我们没事 I-I want us to be.
你没有理由继续生气了啊 You have no reason to still be mad.
我没有生气 I'm not mad.
我只是 I'm... I'm just...
是摩根 It's Morgan.
药物导致詹姆斯上消化道出血 The medication caused James an upper GI bleed.
你找到出血点了吗 Have you localized the source of the bleeding?
正在找 Working on it.
看起来是在胃窦 Seems to be coming from the antrum of the stomach.
我们停了比尼梅替尼 We stopped the Binimetinib.
除了导致出血 On top of causing this,
药物并没能消肿 it hadn't done much to curtail the swelling.
莱瓦医生在哪 Where's Dr. Lever?
这里有一处溃疡性病损 电灼器 There's the ulcerative lesion. Cautery.
斑马鱼 Zebrafish.
它们因为成熟得很快 They're used in medical research
而被用于医疗研究中 because of their quick maturation,
而且84%和人类疾病有关的基因 and 84% of genes associated with human disease
在斑马鱼中都有对应 have a zebrafish equivalent.
你觉得我们应该在斑马鱼的基因组中 You think we should do a transgenic expression
对詹姆斯的突变基因进行转基因表达 of James' ARAF mutation into the zebrafish genome.
给不清楚遗传学的我们翻译一下吧 Translation for those of us without a genetics textbook handy?
把有相同基因突变的斑马鱼当作小詹姆斯样本 We make mini-Jameses, as zebrafish, all with the same disorder.
然后在这些鱼身上测试所有能想到的药物 Then we test every conceivable drug on those fish.
要多久才能开始测试 How long before we can start testing?
如果我们现在植入胚胎 If we implant the embryos now,
可能在明天下午晚些时候开始 probably by late afternoon tomorrow.
快去做 Get going.
肖恩 你跟她一起 你有病理学的经验 Shaun, go with her. You have Path experience.
我知道不就是不 I understand no means no.
如果你不想做爱 If you don't want to have sex,
我接受 I accept that.
但我非常困惑 But I am very confused.
我也是 So am I.
我以为我没事但是... I thought I was fine u-until I...
我按照你的要求让莉亚搬出去 I told Lea to move out, like you wanted.
你说一切都好 You said that things were okay.
但并非如此 我该怎么做才好 They aren't. How do I make them okay?
我不能告诉你 因为我也不知道 I can't tell you, because I don't know.
我在做化疗时 When I was in chemo,
护士们常常逼我喝下那些东西 the nurses used to force that stuff down my throat,
所以我知道你不是因为味道好才喝 so I know you're not drinking it because of the taste.
这是既快速又简单的营养品 It's fast, easy nutrition.
这样你就不会在厕所里吐了 That and you don't end up puking your guts out in the bathroom.
我在这家医院当了十多年的院长 I was president of this hospital for over 10 years.
我交了些朋友 比如清洁工杰克 I made a few friends, including Jack the janitor...
话多 棒球粉丝 超级八卦 Talks a lot, A's fan, horrible gossip.
如果甲氨蝶呤让你恶心 If the methotrexate is making you sick,
我们应该换一种药 we should try another medication.
你怎么能保证你不会在 How can you guarantee that you're not gonna throw up
下次手术中呕吐呢 in the middle of your next surgery?
不会的 It won't happen.
除非我吃了固体食物 Because it only happens if I eat solid food.
而我没吃了 And I stopped.
至少上班时没吃 At least at work.
好多鱼缸啊 That is a lot of fish tanks.
四十个 这样我们可以测试所有可能的药物 Forty. So we can test all of the possible medications for...
你要开派对吗 Are you throwing a party?
希望能开 Hope so.
你还好吗 肖恩 How are you doing, Shaun?
自从你父亲去世后 Since your father passed away?
我不怎么会想起他 I don't think about him very much.
我妈妈 最近去世了 My mom...died recently.
我不知道你是否知道 I-I don't know if you knew that.
她总是突然出现在我脑海里 She pops into my head all the time.
不都是最好的画面 Not always the nicest thoughts.
不爱他们也没关系 It's okay not to love them.
我们的成就与他们无关 They didn't make us who we are.
你妈妈回家了吗 Has your mom gone home?
今晚我们还有一件事要处理 There is one more thing we have to deal with tonight.
拜托 Come on.
你到底能拍多少套片子啊 How many more sets of imaging can you possibly do?
其中一套就是你的舞会礼服 One of these is your prom dress.
我喜欢粉色 但我觉得你穿这两种颜色都很漂亮 I like the pink, but I think you'd look gorgeous in both.
赶快选择吧 Hurry up and choose.
你的约会对象就快到了 Your date'll be here soon.
所有药物都注射完毕 All the medications are in.
那就得花更多的时间等待 看哪种药有效 Which means more waiting to see which medicine works.
耐心等待真难 It's hard to be patient.
你觉得鱼可以控制自己对药物的反应吗 Do you think the fish control how they react to the meds?
不可以 No.
这只是它们身体的反应 It's just how their bodies respond.
昨晚我就是这样的 That's how I felt last night.
我以为我准备好跟你在一起了 I thought I was ready for us to be together,
但我的身体却有不同的反应 but my body had a different response.
我不能消除这种反应 就像这些鱼 I can't turn that response off any more than these fish
不能控制它们的突变对药物的反应一样 can control how their mutation reacts to the medication.
我们的突变 Was our mutation
是我和莉亚去怀俄明州吗 me going to Wyoming with Lea?
你觉得我们能找到合适我们的药物吗 Do you think we can find our right medication?
♪ I found a love ♪
BGM: Perfect by Ed Sheeran
♪ For me ♪
♪ Darling, just dive right in ♪
♪ Follow my lead ♪
♪ I found a girl ♪
♪ Beautiful and sweet ♪
你好美 You look amazing.
♪ I never knew you were the someone waiting for me ♪
你也是 So do you.
♪ 'Cause we were just kids when we fell in love ♪
♪ Not knowing what it was ♪
♪ I will not give you up this time ♪
♪ Darling, just kiss me slow ♪
♪ Your heart is all I own ♪
♪ And in your eyes, you're holding mine ♪
♪ Baby, I'm ♪
♪ Dancing in the dark ♪
♪ With you between my arms ♪
♪ Barefoot on the grass ♪
毕业舞会
♪ Listening to our favorite song ♪
♪ When you said you looked a mess ♪
♪ I whispered underneath my breath ♪
你现在看起来 Looks like you might be feeling
像个幸福的傻瓜 a little idiotic happiness right now.
或许是太感动了 Maybe a touch.
♪ No, no ♪
愿意和舞会国王跳支舞吗 Dance with a prom king?
♪ You look perfect tonight ♪
他心动过速 He's tachycardic.
我们正说着话 他突然就沉默了 We were talking, and then he just stopped.
我们得做心包穿刺 We need to do a pericardial tap.
通知导管室我们要到了 Call the cath lab. Tell them we're coming.
没时间了 我们就在这里做 No time. We're doing it here.
詹姆斯 你胸部疼痛是由于 James, the pain in your chest
心脏周围有太多积液 is from too much fluid around your heart.
我们要在胸腔放置导管 排出积液 We're gonna put a tube into your chest to drain it.
通知肖恩和卡莉 就说我们没时间了 Call Shaun and Carly. Tell them we're running out of time.
♪ Will be loving you till we're 70 ♪
BGM: Thinking Out Loud by Ed Sheeran
♪ And, baby, my heart could still fall as hard at 23 ♪
♪ And I'm thinking about how ♪
♪ People fall in love in mysterious ways ♪
我把安吉的赤脚熊带来了 I brought Angie's Bearfeet Bear.
这总能让她感到... It always makes her feel like sh...
这是毕业舞会 It's...prom.
瑞恩整晚都戴着口罩 Ryan has been wearing his mask all night.
♪ And I just want to tell you I am ♪
♪ So, honey, now ♪
♪ Take me into your loving arms ♪
别让她玩到太晚 Don't let her stay up too late.
♪ Kiss me under the light of a thousand stars ♪
♪ Place your hand on my beating heart? ♪
摩根打了电话来 詹姆斯情况不妙 Morgan called. James isn't doing well.
把SL-327从清单上划掉 Cross SL-327 off the list.
我看见一个... I see one...
不 是两个肿瘤 No, two tumors.
好了 Okay.
我就送你到这里 This is my stop.
待会儿见 I'll see you after.
我爱你 I love you.
我也爱你 妈 I love you, too, Mom.
别担心 好吗 Don't worry. Okay?
我能行 I got this.
我知道你可以 I know you do.
好 Okay.
如果我醒来不认识瑞恩了怎么办 What if I wake up and don't remember Ryan at all?
那... Then...
你就有了重新爱上他的机会 you'll have the chance to fall in love with him all over again.
好了 Okay.
我们只剩五个可选项了 We're down to five potential options.
我不要五个可选项 我只要一个可行的选项 I don't need five potential. I need one actual.
其中两个能最有效控制... There are two that best curb...
选出一个 Choose one.
我们可以试试雷法迈替尼 We should try Refametinib.
它会造成异常细胞生长 It caused abnormal cell growth.
曲美替尼更安全 Trametinib is safer.
但不是绝对安全 Which doesn't mean it's safe.
没有什么绝对安全 Nothing's safe.
你想让我们用哪种药 Which do you want us to do?
曲美替尼 Trametinib.
用这个吧 That's the one.
输入生理盐水 Saline in.
窥镜推向第三心室 Advancing scope toward the third ventricle.
克莱尔 我切断血液供给时 Claire, hold gentle pressure on the tumor
轻轻按住肿瘤 while I cut off its blood supply.
严重出血 We've got some significant bleeding.
调整视野和抽吸器 Adjust the scope and suction.
往上照 Look higher.
隔静脉 这是出血处 Septal vein... There's your bleeder.
灼烧止血 Cauterize away.
微型解剖刀 Micro dissector.
肿瘤无法移动 The tumor's immobile.
我要切除它就会伤到神经束 I can't resect it without injuring the nerve tracts.
会让她昏迷不醒 She'd be comatose.
试试锐解剖 Try sharp dissection.
-找不到平面 -有多糟 - I can't get a plane. -How bad?
肿瘤完全侵入了她的脑丘 It's completely invaded her thalamus.
用抽吸器把切口变薄再切除 Thin it out with a suction aspirator.
粘得太紧了 It's too adherent.
继续的话她会死 If I keep going, I'm gonna kill her.
有什么建议吗 Any ideas?
通知重症监护室 安吉会比预计的早到 Tell ICU Angie will be coming sooner than we planned.
开始缝合吧 Let's close her up.
接下来呢 What next?
再来一轮放化疗吗 Another round of radiation, chemo?
她的癌症 Her carcinoma is
对这些治疗不可能产生反应 unlikely to respond to those therapies.
不 我们要试试 No. We have to try.
安吉会希望与病魔抗争 Angie will want to fight.
她发病了 She's seizing.
给我氯羟去甲安定和狄兰汀 马上 Give me lorazepam and Dilantin, stat.
准备好苯巴比妥和普洛福 Phenobarb and propofol on deck.
你在哭 You're crying.
对 Yes.
为什么 Why?
我在脸书上看到詹姆斯 I found James on Facebook.
他和马乔里想去哥斯达黎加 He and Marjorie want to go to Costa Rica.
他们救助了一只三条腿的狗 叫三脚架 Their dog is a three-legged rescue named Tripod.
他不是一张无生命的图像 他是个人 He's not a slide. He's a person.
他是个好人 He's a good person.
但他可能会死 And he might die.
所以我喜欢待在化验室 This is why I like to stay in the lab.
这话 That...
说出来挺蠢的 Is a very dumb thing to say.
如果你当时待在化验室 If you had stayed in the lab,
詹姆斯可能已经死了 James would probably be dead already.
你的斑马鱼计划给了他一次机会 Your plan with the zebrafish gave him a chance.
这个漂亮 完美的想法 It was a beautiful, perfect idea,
来自一个漂亮 近乎完美的人 from a beautiful, almost perfect person.
你的耳垂大小不一样 Your earlobes are lopsided.
对不起 I'm so sorry.
我们没能救他 We couldn't save her.
瓦伦斯女士 Ms. Valens?
斑马鱼的建议非常好 Nice call on the zebrafish.
关于论文 我们每周碰一次面 About our paper, let's meet weekly.
就每周二在餐厅一起吃午饭时谈吧 I'm thinking lunch every Tuesday in the cafeteria.
很好 Perfect.
我听说了梅伦德斯的病人 I heard about Melendez's patient.
是的 Yeah.
你是对的 You were right.
也许我应该尝试别的药物治我的类风湿性关节炎 I should probably try another medication for my RA.
我要吃固体食物 I need solid food.
克莱尔 等等 Claire? Wait up.
你还好吗 You okay?
没事 就是有点累 Fine. I'm just tired.
你为安吉做的已经很好了 You did an amazing thing for Angie.
你给了她妈妈永远难忘的记忆 You gave her mother a memory that she will have forever.
那也不能弥补她的丧女之痛 Well, it won't make up for the daughter she lost.
你在生气 You're angry.
我没有 我在伤心 I'm not. I am sad.
-你生谁的气 -我没有 - Who are you angry at? - I'm not.
你生我和格拉斯曼的气吗 Are you angry at me and Glassman
因为我们没能救她 because we couldn't save her?
-没有 -生安吉的气 - No! - At Angie?
不 你不能因为一个人死了而生气 No, you can't be mad at someone for dying!
并非如此 你很清楚 That's not true. You know that.
她生病了 She was sick.
而且她很努力想康复 And she was trying to get better.
你费心费力来照顾她 She failed and left you alone,
她却失败了 弃你而去 after you'd spent a lifetime trying to take care of her.
你完全有理由生你母亲的气 You have every reason to be mad at your mother.
我讨厌这种感觉 I hate feeling this way.
我的一生 都在生她的气 My whole life, I've been angry at her,
现在什么都没有改变 and now it will never change.
我不知道如何停止 I don't know how to stop.
可以通过治疗 Therapy will help.
可以让时间冲淡 Time will help.
还有一种方法对我有效 There is one other thing that's worked for me.
我们的「突变」解决了吗 Did we fix our mutation?
你就这点本事吗 That the best you got?